When we knocked down calmodulin in healthy T cells, their KCa3.1 function decreased and they lost their ability to chemotax in an adenosine rich environment, similar to what we had previously reported in cancer T cells. https://t.co/wZIvwG8voK (@scisignal
We have shown previously @scisignal that cytotoxic CD8+ T cells fail to infiltrate the adenosine rich solid tumors and this is because of a functional defect in the KCa3.1 channels in the cancer T cells https://t.co/wZIvwG8voK https://t.co/3IOLjElzpn
RT @ameetchimote: @OncoBites @sara_musetti Also check out our paper in @scisignal that shows that that the high adenosine in tumors inhibit…
@OncoBites @sara_musetti Also check out our paper in @scisignal that shows that that the high adenosine in tumors inhibits the ability of the CD8 T cells to chemotax and therefore infiltrate https://t.co/wZIvwFQU0a Keep up the good work on @OncoBites - I’
@armish @PaulosLab @hammer_lab Pretty cool assay and wonderful experimental design and schematics. Check out our paper @scisignal where we performed 3D chemotaxis on primary T cells in the presence of CXCL12. https://t.co/wZIvwG8voK Congrats the the team!
RT @scisignal: Adenosine inhibits the migration of T cells from cancer patients due to reduced KCa3.1 K+ channel activity https://t.co/Jfuj…
RT @ameetchimote: Honored that our work is featured by @scisignal as #bestof2018 @TMWiseDraper @michael_arnold2 @UCHealthNews @UC_CoMRese…
RT @scisignal: Adenosine inhibits the migration of T cells from cancer patients due to reduced KCa3.1 K+ channel activity https://t.co/Jfuj…
RT @ameetchimote: Honored that our work is featured by @scisignal as #bestof2018 @TMWiseDraper @michael_arnold2 @UCHealthNews @UC_CoMRese…
RT @ameetchimote: Honored that our work is featured by @scisignal as #bestof2018 @TMWiseDraper @michael_arnold2 @UCHealthNews @UC_CoMRese…
RT @scisignal: Adenosine inhibits the migration of T cells from cancer patients due to reduced KCa3.1 K+ channel activity https://t.co/Jfuj…
Honored that our work is featured by @scisignal as #bestof2018 @TMWiseDraper @michael_arnold2 @UCHealthNews @UC_CoMResearch
RT @scisignal: Adenosine inhibits the migration of T cells from cancer patients due to reduced KCa3.1 K+ channel activity https://t.co/Jfuj…
Adenosine inhibits the migration of T cells from cancer patients due to reduced KCa3.1 K+ channel activity https://t.co/JfujIAfmsK @uofcincy @ameetchimote #ionchannels #cancerimmunity #BestOf2018 https://t.co/ONkUVYebU6
RT @2018ici: Hear Laura Conforti @2018ici discuss her study @scisignal about potassium channels and immune surveillance in cancer. https://…
RT @2018ici: Hear Laura Conforti @2018ici discuss her study @scisignal about potassium channels and immune surveillance in cancer. https://…
RT @2018ici: Hear Laura Conforti @2018ici discuss her study @scisignal about potassium channels and immune surveillance in cancer. https://…
Hear Laura Conforti @2018ici discuss her study @scisignal about potassium channels and immune surveillance in cancer. https://t.co/676UfF0PTD
RT @ameetchimote: We are very excited and proud that our new paper is out in the latest issue of @scisignal ! #Immunology #cancer #tcells #…
RT @scisignal: #Adenosine inhibits 3D migration of #Tcells from cancer patients that have reduced KCa3.1 channel activity @uofcincy @ameetc…
#Adenosine inhibits 3D migration of #Tcells from cancer patients that have reduced KCa3.1 channel activity @uofcincy @ameetchimote @TMWiseDraper https://t.co/XqLQadBc4m
RT @humanimmunenews: A Defect in KCa3.1 Channel Activity Limits the Ability of CD8+ T Cells from Cancer Patients to Infiltrate an Adenosine…
RT @humanimmunenews: A Defect in KCa3.1 Channel Activity Limits the Ability of CD8+ T Cells from Cancer Patients to Infiltrate an Adenosine…
@EladSharonMD : It was very nice to meet you today at #AAI2018 . Please check our latest paper in @scisignal https://t.co/K4C3kunXyN
A Defect in KCa3.1 Channel Activity Limits the Ability of CD8+ T Cells from Cancer Patients to Infiltrate an Adenosine-Rich Microenvironment @uofcincy https://t.co/iM3nJL7Mmx
RT @scisignal: Scientists find that boosting the activity of potassium channels restores the migration of #Tcells from cancer patients norm…
RT @scisignal: Scientists find that boosting the activity of potassium channels restores the migration of #Tcells from cancer patients norm…
Scientists find that boosting the activity of potassium channels restores the migration of #Tcells from cancer patients normally inhibited by #adenosine @uofcincy @ameetchimote @TMWiseDraper: https://t.co/XqLQadBc4m https://t.co/jaJK8dYMMq
RT @bemygene: #Research|A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from #cancer patients to infiltrate an adeno…
#Research|A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from #cancer patients to infiltrate an adenosine-rich microenvironment. ➡ https://t.co/iB1jHlRfd3 @sciencemagazine
Thank you @ImmunoSignaling for spreading the word about our paper in @scisignal https://t.co/E43mkaj6Nc
RT @scisignal: #Adenosine inhibits 3D migration of #Tcells from cancer patients that have reduced KCa3.1 channel activity @uofcincy @ameetc…
RT @ameetchimote: We are very excited and proud that our new paper is out in the latest issue of @scisignal ! #Immunology #cancer #tcells #…
RT @ameetchimote: We are very excited and proud that our new paper is out in the latest issue of @scisignal ! #Immunology #cancer #tcells #…
RT @Aenoreth: A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from cancer patients to infiltrate an adenosine-rich m…
RT @AlvaroLladser: A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from cancer patients to infiltrate an adenosine-r…
RT @proteindynamics: A defect in KCa3.1 channel activity limits the ability of CD8 T cells from cancer patients to infiltrate an adenosine…
RT @ameetchimote: We are very excited and proud that our new paper is out in the latest issue of @scisignal ! #Immunology #cancer #tcells #…
RT @ameetchimote: We are very excited and proud that our new paper is out in the latest issue of @scisignal ! #Immunology #cancer #tcells #…
RT @scisignal: #Adenosine inhibits 3D migration of #Tcells from cancer patients that have reduced KCa3.1 channel activity @uofcincy @ameetc…
We are very excited and proud that our new paper is out in the latest issue of @scisignal ! #Immunology #cancer #tcells #ionchannels @michael_arnold2 @UCHealthNews @UC_CoMResearch https://t.co/IQkl4jj6P8
#Adenosine inhibits 3D migration of #Tcells from cancer patients that have reduced KCa3.1 channel activity @uofcincy @ameetchimote @TMWiseDraper https://t.co/XqLQadBc4m https://t.co/UxONMjZLz7
A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from cancer patients to infiltrate an adenosine-rich microenvironment https://t.co/fuAvprIhhL
A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from cancer patients to infiltrate an adenosine-rich microenvironment https://t.co/0rByknnKB9